Prof. Dr. BENSU - KARAHALİL

Eczacılık Fakültesi > Eczacılık Meslek Bilimleri > Farmasötik Toksikoloji

Bilimsel Toplantı - Kongre ve Görevler

Kongre

  • Karakaya,A.E., Şardaş,S., Karahalil,B., Akyol,D. , 1995. The effect of smoking on SCE rate of newborn infants born to smoking mothers., The International Toxicologist "Horizons in Toxicology: Preparing for the 21st Century" Washington, USA.
  • Karahalil, B., Şardaş, S., Akyol, D., Kükner, S., Karakaya, A.E.: The effect of smoking on SCE rate of newborn infants born to smoking mothers, 1st International Meeting on Pharmacy and Pharmaceutical Sciences, September 4-7, Abst. P 145, İstanbul, Turkey, 1994. , 1994. The effect of smoking on SCE rate of newborn infants born to smoking mothers, 1st International Meeting on Pharmacy and Pharmaceutical Sciences, İstanbul, Turkey.
  • Şardaş, S., Karahalil, B.,Karakaya, A.E., Şaşmaz, R.. , 1993. Mutagenic risk in psoriatic patients before and after 8-methoxypsoralen and longwave ultraviolet radiation , 3rd International Symposium on Pharmaceutical Sciences, Ankara University, Faculty of Pharmacy, Ankara, Turkey,
  • Şardaş, S., Karahalil, B.,Ada, M., Karakaya, A.E., Aydın, N,. Şaşmaz, R. , 1993. Evaluation of genotoxicity in patients under antiepileptic and PUVA treatment , 50th European ISSX Meeting Tours, France.
  • Şardaş, S., Karakaya, A.E., Gök, S., Karahalil, B., 1990. Şardaş, S., Karakaya, A.E., Gök, S., Karahalil, B.: Genotoxic risk in the hospital environment. 50th International Congresses of FIP, September 3-7, Abst. P 11, İstanbul, Turkey, 1990. , . 50th International Congresses of FIP İstanbul
  • Şardaş, S., Karakaya, A.E., Karahalil, B.:, 1990. Sister chromatid exchange in nurses and anesthesilogist, , International Congress of the European Association of Poising Control Centers, M, Italy

Kitap ve Editörlük

Kitap

  • Karahalil b, Yıldız F. (2010). Karahalil B.:Advances in Food Biochemistry (Ed. Fatih Yıldız) Pharmacogenomics and Toxicogenomics in Food Chemicals, Taylor&Francis, CRC Press., 2010.. Karahalil B.:Advances in Food Biochemistry (Ed. Fatih Yıldız) Pharmacogenomics and Toxicogenomics in Food Chemicals, Taylor&Francis, CRC Press., 2010. Taylor&Francis.
  • Yıldız, F., Adlercreutz, H. (2006). Phytoestrogens in Functional Foods, . Phytoestrogens in Functional Foods USA. Taylor&Francis.

Editörlük

  • (2011). Frontiers in Toxicogenomics,
  • (2007). Toxicology and Industrial Health,
  • (2005). FABAD,

Makaleler

SCI, SCI-EXP., SSCI, AHCI Tarafından Taranan Makaleler

  • Karahalil B, Ulukaya M, Alp O. (2012). Pilot Study of Environmental Monitoring of Konya Region near Abandoned Mercury Mine in Turkey. . Bull Environ Contam Toxicol. , 88(150).
  • Kesimci E, Engin AB, Kanbak O, Karahalil B. (2012). Association between ABCB1 gene polymorphisms and fentanyl's adverse effects in Turkish patients undergoing spinal anesthesia.. Gene, 493(273).
  • Türkan H , Aydin A, . Sayal A, Karahalil B. (2011). The Effect of Sevoflurane and Desflurane on Markers of Oxidative Status in Erythrocyte. TIH, 27(181).
  • Yağar S, Yavaş S, Karahalil B. (2011). The role of the ADRA2A C1291G genetic polymorphism in response to dexmedetomidine on patients undergoing coronary artery surgery.. Mol Biol Rep. , 38(3383).
  • Karahalil B, Kesimci E, Emerce E, Gumus T, Kanbak O. (2011). The impact of OGG1, MTH1 and MnSOD gene polymorphisms on 8-hydroxy-2'-deoxyguanosine and cellular superoxide dismutase activity in myocardial ischemia-reperfusion. . Mol Biol Rep. , 38(2427).
  • Engin AB, Karahalil B, Engin A, Karakaya AE. (2011). DNA repair enzyme polymorphisms and oxidative stress in a Turkish population with gastric carcinoma. . Mol Biol Rep., 38(5379).
  • Dhawan A, Shanker R, Laffon B, Tajes JF, Fuchs D, van der Laan G, van Broekhuizen P, Becker H, Moriske HJ, Teixeira JP, Carriere M, Herlin-Boime N, Engin AB, Coskun E, Karahalil B. . (2011). NanoLINEN: nanotoxicology link between India and European Nations. . J Biomed Nanotechnol., 7(203).
  • Türkan H, Aydin A, Sayal A, Eken A, Akay C, Karahalil B. (2011). Oxidative and antioxidative effects of desflurane and sevoflurane on rat tissue in vivo. . Arh Hig Rada Toksikol., 62(113).
  • Gopalan RC, Emerce E, Wright CW, Karahalil B, Karakaya AE, Anderson D. (2011). Effects of the anti-malarial compound cryptolepine and its analogues in human lymphocytes and sperm in the Comet assay. . Toxicol Lett., 207(322).
  • Engin AB, Karahalil B, Karakaya AE, Engin A. (2011). Association between XRCC1 ARG399GLN and P53 ARG72PRO polymorphisms and the risk of gastric and colorectal cancer in Turkish population.. Arh Hig Rada Toksikol., 62(207).
  • Karahalil B, Emerce E, Kocabas NA, Akkas E (2010). Associations between GSTM1 and OGG1 Ser326Cys polymorphisms and smoking on chromosomal damage and birth growth in mothers. . Mol Biol Rep., 38(2911).
  • Karahalil B, Polat S, Senkoylu A, Bölükbaşı S. (2010). Evaluation of DNA damage after tourniquet-induced ischaemia/reperfusion injury during lower extremity surgery, . Injury, 41(1003).
  • Engin AB, Karahalil B, Engin A, Karakaya AE. . (2010). Oxidative stress, Helicobacter pylori, and OGG1 Ser326Cys, XPC Lys939Gln, and XPD Lys751Gln polymorphisms in a Turkish population with colorectal carcinoma. . Genet Test Mol Biomarkers, 14(559).
  • Karahalil B., Bohr VA, De Souza-Pinto, NC. (2010). Base Excision Repair Activities Vary in Human Lung Cancer Cells and Corresponding Normal Controls. Anticancer Res., 30(4963).
  • Karahalil B, Gumus T, Emerce E, Izdes S, Kanbak O, Kesimci E. (2009). Comet assay in evaluating DNA damage associated with ischaemia-reperfusion injury in patients undergoing coronary surgery. . Arh Hig Rada Toksikol., 60(307).
  • Kaymak C, Karahalil B, Ozcan NN, Oztuna D (2008). Association between GSTP1 gene polymorphism and serum alpha-GST concentrations undergoing sevoflurane anaesthesia. Eur J Anaesthesiol, 25(193).
  • Karahalil B, Emerce E, Koçer B, Han S, Alkiş N, Karakaya AE. (2008). The association of OGG1 Ser326Cys polymorphism and urinary 8-OHdG levels with lung cancer susceptibility: a hospital-based case-control study in Turkey. . Arh Hig Rada Toksikol., 59(241).
  • Karahalil B, Coskun E, Emerce E. (2008). ADRA2A polymorphism and smoking in a Turkish population. . TIH, 24(171).
  • Au WW, Sardas S, Karakaya AE, Karahalil B (2008). Vth International Conference on Environmental Mutagens in Human Populations: introduction. . Mutation Res., 659(2-3).
  • Karahalil, B., Aykanat, B., Ertaş, N. (2007). Dental lead levels in children from two different urban and suburban areas of Turkey. . Int. J Hyg. Environ. Health , 210(107).
  • İmam, Z.S, Karahalil, B., Hogue, B.A., Souza-Pinto, N.C., Bohr, V.A. (2006). Mitochondrial and nuclear DNA-repair capacity of various brain regions in mouse is altered in an age-dependent manner. .. Neurobiol Aging, 27(1129).
  • Kocabaş N.A., Karahalil, B. (2006). Kocabaş N.A., Karahalil, B.: XRCC1 Arg399Gln Genetic Polymorphism in a Turkish Population. Int. Toxicol., 25, 419-422, 2006.. Kocabaş N.A., Karahalil, B.: XRCC1 Arg399Gln Genetic Polymorphism in a Turkish Population. Int. Toxicol., 25, 419-422, 2006., 25(419).
  • Karahalil, B., Kocabaş, NA, Özçelik, T. (2006). Karahalil, B., Kocabaş, NA, Özçelik, T.: DNA Repair Gene Polymorphisms and Bladder Cancer Susceptibility in a Turkish Population, Anticancer Res., 26, 4955-4958, 2006.. Karahalil, B., Kocabaş, NA, Özçelik, T.: DNA Repair Gene Polymorphisms and Bladder Cancer Susceptibility in a Turkish Population, Anticancer Res., 26, 4955-4958, 2006., 26(4955).
  • Karahalil, B., Yağar, S., Özin, Y. (2006). Release of α-glutathione s-transferase (α-GST) and hepatocellular damage induced by Helicobacter pylori and eradication treatment. Curr. Drug Safety, 2(43).
  • Karahalil, B.,Yağar, S.,Bahadır, G.,Şardaş, S. (2005). Evaluation of genotoxic effects of Diazepam and Propofol by Chromosomal Aberration Assay in Cardiac Patients. Mutation Res., 581(181).
  • Karahalil, B Aygün Kocabaş, N. (2005). hOGG1 Ser326Cys genetic polymorphism in a Turkish population. .. Arch Toxicol., 79(377).
  • Karahalil, B., Rahravi, H., Ertaş, N., Karakaya, A.E. (2005). Examination of urinary mercury levels in dentists using cold-vapour atomic absorption spectrometry and mercury toxicity,.. Hum. Exp. Toxicol. , 24(383).
  • Stuart, J., Karahalil, B.,Barbara, H., Souza-Pinto, N., Bohr, V. (2004). Mitochondrial and nuclear DNA base excision repair are affected differently by caloric restriction,. FASEB J, , 18(595).
  • Jensen, A., Calvayrac, G., Karahalil, B., Bohr, V.A., Stevnsner, T. (2003). Mammalian OGG1 incises 8-oxoadenine opposite cytosine in nuclei and mitochondria, while a different glycosylase incises 8-oxoadenine opposite guanine in nuclei. . J Biol. Chem. , 278(1954).
  • Karahalil,B., Souza-Pinto, N., Parsons, J.L., Elder, .H., Bohr,V. (2003). Compromised incision of oxidised pyrimidine in liver mitochondria of mice deficient in NTH1 and OGG1 glycosylases . J Biol. Chem, 278(33701).
  • Karahalil B., Şardaş S., Kocabaş N.A., Alhayıroğlu E., Karakaya, A.E., Civelek, E (2002). Chromosomal aberrations under basal conditions and after treatment with X-ray in human lymphocytes as related to the GSTM1 genotype. Mutation Res.. , 515(135).
  • Burgaz, S., Demircigil, G.C., Karahalil, B., Karakaya, A.E.: (2002). Chromosomal damage in peripheral blood lymphocytes of traffic policemen and taxi drivers exposed to urban air pollution. Chemosphere, . , 47(57).
  • Karahalil, B., Hogue, B.A., de Souza-Pinto, N.C., Bohr, V. A. (2002). Base excision repair capacity in mitochondria and nuclei:tissue-specific variations. FASEB J, 16(1895).
  • Biri, A., Civelek, E., Karahalil, B., Sardas, S. (2002). Assessment of DNA damage in woman using oral contraceptives. Mutation Res., 521(113).
  • Kocabaş, N. A., Karahalil, B., Karakaya, A. E., Şardaş, S. (2000). Influence of GSTM1 genotype on comet assay and chromosome aberrations after induction by bleomycin in cultured human lymphocytes. Mutation Res, 469(199).
  • Burgaz, S., Karahalil, B., Canlı, Z.,Terzioglu, F.,Ançel, G., Anzion, R.B.M., Bos, R.P., Hüttner, E.: (2000). Assessment of genotoxic damage in nurses occupationally exposed to antineoplastics by the analysis of chromosomal aberrations. Hum. Exp. Toxicol., 21(129).
  • Urinary cyclophosphamide excretion and micronuclei frequencies in peripheral lymphocytes and in exfoliated buccal epithelial cells of nurses handling antineoplastics, (1999). Urinary cyclophosphamide excretion and micronuclei frequencies in peripheral lymphocytes and in exfoliated buccal epithelial cells of nurses handling antineoplastics. ,Mutation Res, 439(97).
  • Karahalil., B., Karakaya, A.E., Burgaz., S. (1999). The micronucleus assay in exfoliated buccal cells: application to occupational exposure to polycyclic aromatic hydrocarbons. . Mutation Res, 442(29).
  • Karahalil, B., Roldan-Arjona, T., Dizdaroğlu, M. (1998). Substrate specificity of Schizosaccharomyces pombe Nth protein for products of oxidative DNA damage, . Biochemistry. , 37(590).
  • Karahalil, B., Girard, P., Boiteux, S., Dizdaroğlu, M. (1998). Substrate specificity of the Ogg 1 protein of Saccharomyces cerevisiae: Excision of guanine lesions produced in DNA by ionizing radiation- or metal ion/hydrogen peroxyde-generated free radicals, . Nucleic acid Res., 26(1228).
  • . Karahalil, B., Burgaz, S., Fişek, G., Karakaya, A.E.: (1998). Biological monitoring of young workers exposed to polycyclic aromatic hydrocarbons in engine repair workshops. Mutation Res., , 412(261).
  • Burgaz, S., Erdem, O., Karahalil, B., Karakaya, A.E (1998). Cytogenetic biomonitoring of workers exposed to bitumen fumes. utation Res., 419(123).
  • Excision of products of oxidative DNA base damage by human NTH 1 protein (1998). Excision of products of oxidative DNA base damage by human NTH 1 protein. Biochemistry, 38(243).
  • Karakaya,A.E., Karahalil, B., Yılmazer,M., Aygün,N., Şardaş,S., Burgaz,S. (1997). Evaluation of genotoxic potential of styrene in furniture workers using unsaturated polyester resins. Mutation Res., 392(261).
  • Şentürker, S., Karahalil, B., İnal, M., Yılmaz, H., Müslümanoğlu, H., Gedikoğlu, G., Dizdaroğlu, M.: (1997). Oxidative DNA base damage and antioxidant enzyme levels in childhood acute lymphoblastic leukemia . FEBS Letters, 416(286).
  • Şardaş, S., Karahalil, B.,Akyol, D., Kükner, S., Karakaya, A.E (1995). The effect of smoking SCE rate of newborn to smoking mothers,. Mut Res, 341(249).
  • Şardaş, S., Karahalil, B.,Karakaya, A.E., Şaşmaz, R (1994). Mutagenic risk in psoriatic patients before and after 8-methoxypsoralen and longwave radiation. Mutation Res, 312(79).

Ödül - Proje - Buluş

Ödül

  • TÜBA destekli Loreal Genç Bilim Kadını Ödülü (2007)
  • TÜBİTAK Teşvik Ödülü (2006)
  • 2014 Türk Eczacılar Birliği Bilim Ödülü (1960)

Proje

  • ---1989 Eczacılık Fakültesi –Fakülte birincisi 1. 2006 TÜBİTAK Teşvik Ödülü 2. 2007 LOREAL TÜBA Hakemli Genç Bilim Kadınları Destek Bursu 3. Amerika Birleşik Devletleri-Maryland, Ulusal Standartlar ve Teknoloji Enstitüsü (NIST)’nden araştırma bursu (3 ay) 4. Almanya-Gatersleben, IPK genetik enstitüsü’nden araştırma bursu (1,5 ay) 5. NewIndigo Network Pilot Programme, Award of NPP grant for NanoLINEN (Nanotoxicology link between India and European Nations), Avrupa Koordinatörü, 2010. 6. Ulusal Standartlar ve Teknoloji Enstitüsü (National Institute of Standards and Technology; NIST), 1997 Ocak-Nisan, Maryland-USA. 7. Bitki Genetiği Araştırma Enstitüsü (Institute of Plant Genetics and Crop Plant Research; IPK), 1996 Kasım-1997 Kasım (2 ziyaret, toplam 2 ay) Gatersleben-Almanya. 8. Paterson Kanser Araştırma Enstitüsü (Paterson Institute for Cancer Research, Christie Hospital NHS Trust), 2002 Ocak (iki hafta) Manchester-İngiltere. 9. Ulusal Sağlık Enstitüsü (National Institute of Health; NIH), Ulusal Yaşlanma Enstitüsü, Gerontoloji Araştırma Merkezi, Moleküler Biyoloji Laboratuvarı (National Institute of Aging, Gerontology Research Center, Laboratory of Molecular Biology), 2 yıl (2001-2003), USA. 10. Ulusal Sağlık Enstitüsü (National Institute of Health; NIH), Ulusal Yaşlanma Enstitüsü, National Institute of Health (NIH), National Institute of Aging, Moleküler Gerontoloji Laboratuvarı, (İki ay; Temmuz-Ağustos 2009), USA. (1960)